To quote Manohla Dargis for the New York Times:
One of the world’s oldest films, “Sneeze,” is a gift that keeps on giving. Shot in 1894 and about as long as an achoo, it shows a mustachioed gent emitting a single sneeze, a kerchief clutched in one hand. The film was made by W.K.L. Dickson and the sneeze delivered by Fred Ott. Working in Thomas Edison’s New Jersey studio, they gave us the first celluloid sneeze, an open-mouth exhalation that was meant to be humorous but today seems ominous. Cover your mouth! I yelled when I looked at it again.